This Shiny application accompanies the manuscript titled 'The genetic architecture of gene expression in peripheral blood', by Lloyd-Jones et al., published in The American Journal of Human Genetics (DOI:http://dx.doi.org/10.1016/j.ajhg.2016.12.008). If you would like to use any of the results displayed or downloaded from this page in a publication, please cite this work. For further questions, please contact either of the corresponding authors at firstname.lastname@example.org or email@example.com. This app was developed by Alex Holloway and Luke Lloyd-Jones.
If you are interested in genetic correlations between these genes please see the below link and the accompanying paper in Nature Communications titled 'Genetic correlations reveal the shared genetic architecture of transcription in human peripheral blood' DOI:10.1038/s41467-017-00473-z.Genetic correlations Shiny app
Summary-data-based Mendelian Randomization
The summary statistics from the CAGE eQTL analysis are also available for use with the Summary-data-based Mendelian Randomization (SMR) method of Zhihong Zhu et al. (2016) 'Integration of summary data from GWAS and eQTL studies predicts complex trait gene targets'. Nature Genetics, 48: 481-487. Please see the below link for access to these summary statistics in the SMR binary format.SMR CAGE eQTL data